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・ Membrane method
・ Membrane mineralocorticoid receptor
・ Membrane mirror
・ Membrane models
・ Membrane nanotube
・ Membrane osmometer
・ Membrane oxygenator
・ Membrane paradigm
・ Membrane potential
・ Membrane Pro-X carboxypeptidase
・ Membrane progesterone receptor
・ Membrane protein
・ Membrane Protein Structural Dynamics Consortium
・ Membrane reactor
・ Membrane roofing
Membrane ruffling
・ Membrane sex steroid receptor
・ Membrane stabilizing effect
・ Membrane steroid receptor
・ Membrane structure
・ Membrane switch
・ Membrane technology
・ Membrane Theory
・ Membrane theory of shells
・ Membrane topology
・ Membrane transport
・ Membrane transport protein
・ Membrane vesicle trafficking
・ Membrane-associated guanylate kinase
・ Membrane-bound transcription factor site-1 protease


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Membrane ruffling : ウィキペディア英語版
Membrane ruffling

Membrane ruffling (also known as cell ruffling) is the formation of a motile cell surface that contains a meshwork of newly polymerized actin filaments. It can also be regarded as one of the earliest structural changes observed in the cell. The GTP-binding protein Rac is the regulator of this membrane ruffling. Changes in the Polyphosphoinositide metabolism and changes in Ca2+ level of the cell may also play an important role. A number of actin-binding and organizing proteins localize to membrane ruffles and potentially target to transducing molecules.
==Characteristic feature of migrating cells==
Membrane Ruffling is a characteristic feature of many actively migrating cells. When the membrane is unable to attach to the substrate, the membrane protrusion is recycled back into the cell. The ruffling of membranes is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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